Urinary Free Bisphenol A and Bisphenol A-Glucuronide Concentrations in Newborns

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Serial Free Bisphenol A and Bisphenol A Glucuronide Concentrations in Neonates.

OBJECTIVE To determine the balance of metabolism of free bisphenol A (BPA) to the inactive conjugate, BPA glucuronide (BPAG), in neonates. STUDY DESIGN Free BPA and BPAG concentrations were measured in 78 urine samples collected between December 2012 and August 2013 from a cohort of 44 healthy full term (≥ 37 weeks' gestation) neonates at 2 intervals (3-6 days and 7-27 days of age). A questio...

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Variability and Predictors of Urinary Bisphenol A Concentrations during Pregnancy

BACKGROUND Prenatal bisphenol A (BPA) exposure may be associated with developmental toxicity, but few studies have examined the variability and predictors of urinary BPA concentrations during pregnancy. OBJECTIVE Our goal was to estimate the variability and predictors of serial urinary BPA concentrations taken during pregnancy. METHODS We measured BPA concentrations during pregnancy and at ...

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Urinary bisphenol A and plasma hormone concentrations in male workers exposed to bisphenol A diglycidyl ether and mixed organic solvents.

AIMS To evaluate effects of exposure to bisphenol A diglycidyl ether (BADGE) on urinary excretion of bisphenol A, and plasma gonadotrophic hormones and testosterone in male epoxy resin sprayers. METHODS Cross sectional study of 42 workers whose job was to spray epoxy resin hardening agents including BADGE and mixed organic solvents, and 42 matched control workers without BADGE use in the same...

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In isolated hepatocytes, the environmental estrogen bisphenol A (BPA) is metabolized into a mono-glucuronide and a glucuronide/sulfate diconjugate. Little is known about the fate of the diconjugate in the liver. The present study focused on the metabolism and dispostion of BPA diconjugate in the liver using a perfusion method. In Sprague-Dawley rats, BPA (15,150 or 1,500 nmol) was applied into ...

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ژورنال

عنوان ژورنال: The Journal of Pediatrics

سال: 2013

ISSN: 0022-3476

DOI: 10.1016/j.jpeds.2012.11.083